Glutathione (Reduced GSH) – 500mg-1500mg

Glutathione (Reduced GSH)

Glutathione (GSH), specifically in its Reduced Form, is a tripeptide composed of Glutamate, Cysteine, and Glycine. In the landscape of advanced cellular biology and toxicology research, Glutathione is recognized as the most abundant and essential endogenous antioxidant. It serves as the cornerstone of the cell’s defense system, maintaining the Redox (Reduction-Oxidation) Homeostasis and protecting vital cellular components from damage caused by reactive oxygen species (ROS), free radicals, and peroxides. It provides researchers with an indispensable experimental tool to investigate metabolic detoxification, the modulation of immune responses, and the molecular pathways of aging and neuroprotection.

Our Glutathione is processed in an ISO 9001:2015 certified environment utilizing high-precision purification and stabilization technologies. We achieve an ultra-high chemical purity of ≥99%, ensuring the compound is in its active Reduced State for maximal biological efficacy. This rigorous production standard ensures the absence of oxidized glutathione (GSSG) contaminants and heavy metals, guaranteeing the consistency and structural fidelity required for sensitive enzymatic assays and longitudinal oxidative stress studies.

Research Applications & Mechanisms

Oxidative Redox Homeostasis

Investigating the ratio of GSH to GSSG to study the cellular response to oxidative stress and the maintenance of thiol-disulfide equilibrium.

Phase II Detoxification Pathways

Researching the role of Glutathione S-transferases (GST) in investigating the conjugation and neutralization of xenobiotics and heavy metals.

Mitochondrial & DNA Protection

Studying the mechanisms through which GSH protects mitochondrial DNA and membrane integrity from oxidative lipid peroxidation.

Immunomodulatory Signaling

Exploring the influence of Glutathione levels on T-cell proliferation and the regulation of inflammatory cytokine production in research models.

Technical Specifications

Key Features & Quality Assurance

Advanced Lyophilization Stability

Our proprietary vacuum-sealing process ensures the Glutathione powder surface is perfectly smooth, flat, and delicate. This uniform “cake” structure ensures rapid, clear reconstitution and protects the reduced thiol group from premature oxidation during storage.

Active Thiol Content Verification

Every batch is strictly verified to ensure the highest ratio of Reduced GSH, providing predictable and powerful antioxidant activity in all experimental designs.

Reconstitution & Storage

Reconstitution Guide

• Preparation: Allow the vial to reach room temperature. Centrifuge for 30-60 seconds to ensure the Glutathione cake is at the base.

• Solvent: Reconstitute with Sterile Water or 0.9% Normal Saline.

• Technique: Gently introduce the diluent against the vial wall. DO NOT SHAKE; swirl gently until the solution is clear and transparent.

Storage Protocols

• Long-term: Store at -20°C (Maintains potency for up to 24 months).

• Short-term: Stable at 2–8°C for up to 3 months.

• Post-Reconstitution: Store at 2–8°C and utilize within 48-72 hours for optimal antioxidant activity. Reduced Glutathione is sensitive to oxidation once in solution.

Shipping & Documentation

• Global Logistics: Shipped in discreet, secure packaging to maintain the chemical integrity of the Reduced Glutathione compound.

• Verified Quality: A batch-specific COA and HPLC reports are available for every order.

• Reshipment Policy: We provide a guaranteed reshipment policy for any lost or customs-intercepted orders ().

⚠️ Research Disclaimer

Product-Specific Safety Notice: This Glutathione (Reduced Form) is strictly for laboratory research and analytical purposes. It is NOT intended for human or veterinary administration. All research must be conducted by qualified professionals.

Scientific Resources & References

• Comprehensive chemical, structural, and antioxidant-related data for Glutathione (GSH) .
• Biological function, metabolic pathways, and curated biochemical role information for .

🔍 Deep Dive Research

• [Technical Guide]: Preserving the Reduced State: Best Practices for Glutathione Reconstitution

• [Redox Study]: The Master Protector: Exploring Reduced Glutathione in Modern Cytological Research